Breast Care A-Z · Procedure · NSM

Nipple-sparing mastectomy

also: NSM, nipple-areola-sparing mastectomy

A nipple-sparing mastectomy removes the breast tissue while preserving the breast skin and the nipple, giving the most natural cosmetic result when combined with immediate reconstruction. You may be considering mastectomy and want to know whether it is an option for you — the eligibility criteria are specific.

Quick answers

Will my nipple feel normal afterwards?

Sensation in the preserved nipple is usually reduced and sometimes absent — the small nerves supplying the nipple are often disturbed during the operation. Some sensation may return over months, but full pre-operative sensation typically does not. This is one of the realistic considerations to weigh, particularly in risk-reducing surgery where there is no cancer to push the decision.

Can I have NSM if I have already had children?

Yes. Pregnancy and breastfeeding history do not affect NSM eligibility. Future breastfeeding is not possible after any mastectomy, including NSM.

What if my nipple has poor blood supply during the operation?

Sometimes during surgery the blood supply to the preserved nipple looks compromised. The surgeon's options include converting to a skin-sparing approach (removing the nipple) or planning a second-stage adjustment. The decision is made during the operation based on what the team sees.

Nipple-Sparing Mastectomy -- Breastory Encyclopaedia Plate LXI Plate covering NSM: indications, technique, oncological safety, patient selection, and comparison with standard mastectomy. SURGERY · OPERATIVE PROCEDURES PLATE LXI nipple-sparing mastectomy NSM · NAC-preserving mastectomy mastectomy technique preserving the nipple-areola complex for optimal cosmetic outcomes and reduced psychological impact in carefully selected patients FIG 01 -- Standard mastectomy (left) vs Nipple-Sparing Mastectomy (right) chest wall pec. major NAC removed STANDARD MASTECTOMY pec. major (intact) implant / expander NIPPLE-SPARING MASTECTOMY NAC preserved inframammary fold incision i -- inframammary fold incision (NSM preferred) ii -- nipple-areola complex (preserved) iii -- breast tissue removed (subcutaneous plane) iv -- pectoral muscle (intact) v -- immediate implant / expander in situ Patient selection criteria Tumour >2cm from NAC No NAC involvement on MRI No Paget's disease of nipple No inflammatory breast cancer Prophylactic (BRCA risk-reducing) Normal nipple cytology intraoperatively Oncological safety checks Retroareolar biopsy Frozen section intraoperatively If positive NAC removed -- converts to SSM If negative NSM proceeds safely FIG 02 -- NSM vs Standard mastectomy: clinical comparison Feature NSM Standard Mastectomy NAC preserved Yes No Cosmetic result Superior Requires reconstruction Patient satisfaction Higher Good with reconstruction Incision Inframammary / lateral Periareolar ellipse Oncological safety Equivalent if criteria met Standard NAC recurrence 1-2% Not applicable Nipple sensation Partially preserved Lost Breastfeeding Not possible Not possible Reconstruction Usually immediate Immediate or delayed Prophylactic use Ideal (BRCA) Used but NAC loss is burden FIG 03 -- NSM approaches and reconstruction options Approach Incision site Advantage Inframammary fold Along breast crease Hidden scar, excellent access Lateral radial Axillary approach Hidden, SLNB same incision Periareolar Around NAC border Short scar, some NAC risk Vertical Inferior pole Useful for large breasts Endoscopic-assisted Small port incisions Minimal scarring Robotic NSM Robot-assisted Emerging technique With immediate implant Single-stage if <350ml Reduced operations With tissue expander Two-stage More control over result With DIEP flap Autologous + NSM Warm, natural tissue FIG 04 -- NSM clinical pathway 1 Indication: BRCA / early cancer >2cm 2 MRI: extent and NAC involvement 3 MDT + patient consent 4 Intraop retroareolar frozen section 5 NSM + immediate reconstruction 6 Adjuvant treatment as indicated FIG 05 -- Related procedures and outcomes NSM for early breast cancer NSM for BRCA risk reduction NSM with immediate implant NSM with DIEP flap Nipple reconstruction (if NAC lost) Failed NSM -- SSM conversion FIG 06 -- Key statistics NAC recurrence rate ~1-2% with correct selection [1] Patient satisfaction higher vs standard mastectomy [2] ~50% of risk-reducing mastectomies are NSM [3] Equivalent oncological outcomes when criteria met [4] References 1. de Alcantara Filho P et al. NAC recurrence after NSM. Breast Cancer Res Treat 2011 2. Didier F et al. NSM quality of life. Plast Reconstr Surg 2009 3. NICE NG101. Early breast cancer 2023 4. Yao K et al. NSM oncologic safety. Ann Surg Oncol 2015 5. Galimberti V et al. Nipple-sparing mastectomy. Breast 2021 Clinically authored by Dr Fiona Tsang-Wright , FRCS (Gen Surg) GMC 4549831 · ORCID 0000-0003-4801-026X
Visual Reference · Nipple-sparing mastectomy
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Definition
A nipple-sparing mastectomy is a mastectomy that removes all the breast tissue but preserves both the breast skin envelope and the nipple-areolar complex, allowing immediate reconstruction with the most natural-looking cosmetic outcome.
Comparable Local recurrence rate vs skin-sparing mastectomy in selected patients (systematic-review evidence) 1 2

Common questions The questions patients ask first

Will my nipple feel normal afterwards?
Sensation in the preserved nipple is usually reduced and sometimes absent — the small nerves supplying the nipple are often disturbed during the operation. Some sensation may return over months, but full pre-operative sensation typically does not. This is one of the realistic considerations to weigh, particularly in risk-reducing surgery where there is no cancer to push the decision.
Can I have NSM if I have already had children?
Yes. Pregnancy and breastfeeding history do not affect NSM eligibility. Future breastfeeding is not possible after any mastectomy, including NSM.
What if my nipple has poor blood supply during the operation?
Sometimes during surgery the blood supply to the preserved nipple looks compromised. The surgeon's options include converting to a skin-sparing approach (removing the nipple) or planning a second-stage adjustment. The decision is made during the operation based on what the team sees.
Is NSM safe for cancer cases?
For carefully selected cancer cases — where the cancer is not close to the nipple and the patient and anatomy are suitable — NSM has equivalent oncological outcomes to skin-sparing mastectomy3. The selection criteria matter; NSM is not appropriate for every cancer4.

A nipple-sparing mastectomy is a mastectomy that removes all the breast tissue but preserves both the breast skin envelope and the nipple-areolar complex, allowing immediate reconstruction with the most natural-looking cosmetic outcome.

NSM is the most cosmetically favourable form of mastectomy when patient anatomy and the cancer’s position allow it. It is most commonly used for risk-reducing mastectomy (where there is no cancer in the breast) and for selected cancer cases where the tumour is well away from the nipple.

Orientation Why you might be reading about this

You may be considering mastectomy and want to understand whether nipple-sparing technique is an option for you. The cosmetic difference between nipple-sparing and skin-sparing mastectomy is meaningful, and the eligibility criteria are specific. This page explains who NSM is suitable for and what trade-offs are involved.

Related terms: Mastectomy · Skin-sparing mastectomy · Risk-reducing mastectomy · Implant reconstruction · DIEP flap

How it differs How NSM differs from other mastectomy types

The key difference is what is removed versus what is preserved:

Simple mastectomy Skin-sparing mastectomy Nipple-sparing mastectomy
Breast tissue removed Yes Yes Yes
Skin envelope preserved No Yes Yes
Nipple-areolar complex preserved No No Yes
Suitable for immediate reconstruction Possible but harder Yes Yes — best cosmetic result

The cosmetic outcome with nipple-sparing technique plus immediate reconstruction is usually the closest a mastectomy result gets to a natural breast — both the skin envelope and the nipple are preserved on the patient’s own tissue.

Suitability When NSM is suitable

Eligibility depends on three factors:

1. The cancer (where one exists)

For cancer surgery, NSM is suitable when4:

  • The cancer is not close to the nipple — typically more than 2 cm away on imaging.
  • There are no signs of nipple involvement clinically (Paget’s disease, nipple discharge from the cancer, retraction).
  • The cancer can be safely cleared with the planned operation while preserving the nipple.

For risk-reducing mastectomy, where there is no cancer, NSM is the default approach where anatomy allows.

2. The breast anatomy

NSM works best in:

  • Smaller-to-moderate breast size — very large breasts can compromise blood supply to the preserved nipple.
  • Breasts that are not very ptotic (drooping) — significant ptosis makes nipple preservation harder, though it is still sometimes possible with technique adjustments.
  • Patients without significant prior surgery that may have disrupted the blood supply to the nipple.

3. The patient

  • Non-smoker (or able to stop for several weeks around the surgery) — smoking significantly increases the risk of nipple loss from compromised blood supply4.
  • Body mass index within a reasonable range — very high BMI is associated with higher complication rates4.

Where any of these factors makes nipple preservation unsafe, skin-sparing mastectomy is the alternative — preserving the skin envelope but removing the nipple1. Nipple reconstruction can be offered later as a smaller day-case procedure.

The procedure What the operation involves

  • Anaesthetic: general anaesthetic.
  • Incision: usually placed in the inframammary fold (under the breast), the lateral chest, or around part of the areolar edge. The incision is hidden as much as possible.
  • Length of operation: depends on the reconstruction. NSM with implant-based reconstruction typically takes 2–3 hours per side2; with DIEP, 6–8 hours.
  • Hospital stay: 1–2 nights for implant-based reconstruction; 4–5 nights for DIEP.
  • Reconstruction: almost always immediate — the preserved skin envelope is filled with an implant or autologous tissue at the same operation.

For more on the practice’s pathway, see mastectomy and risk-reducing mastectomy.

Outcomes Outcomes and trade-offs

What is preserved

  • The skin envelope — including the natural breast contour after reconstruction.
  • The nipple and areola — preserved on their own blood supply, so they remain alive and (often) sensate.
  • Cosmetic result — usually the closest to the original breast.

What is altered

  • Nipple sensation — usually reduced, sometimes absent. Some sensation may return over months.
  • Nipple appearance — the nipple may sit slightly differently after reconstruction; revision can sometimes refine this at a later operation.
  • Risk of nipple loss — a small percentage of preserved nipples lose their blood supply and must be removed at a later operation. The risk is higher in smokers, in very large breasts, and in patients having radiotherapy after surgery4.

Cancer-specific considerations

For cancer cases, the small theoretical concern is that residual breast tissue might remain behind the preserved nipple. In practice, with careful surgical technique, recurrence rates after NSM for cancer are similar to those after skin-sparing mastectomy in patients selected appropriately3. NSM is not recommended where the cancer is close to the nipple4.

At consultation What to discuss at consultation

If NSM is being considered:

  • Whether your specific anatomy and cancer (if applicable) make NSM suitable — not every patient is a candidate.
  • The reconstruction options — implant-based or autologous, immediate.
  • The realistic cosmetic outcome — usually shown at consultation with photographs of a range of results.
  • The risk of nipple loss — small but real, particularly relevant if you smoke or have other risk factors.
  • Sensation — what to expect.

Resources Further reading

Sources & guidance

Every figure on this page is anchored to a published source. Tap a number in the text or below to jump to the reference.

  1. guidance Association of Breast Surgery (ABS). Best Practice Guidelines: surgical management of breast cancer. London: ABS. 2022 https://www.nice.org.uk/guidance/ng101 Cited for: UK best-practice for mastectomy techniques, including indications and contraindications for nipple-sparing mastectomy.
  2. guidance Association of Breast Surgery / British Association of Plastic, Reconstructive and Aesthetic Surgeons. Oncoplastic Breast Reconstruction: Guidelines for Best Practice. London: ABS / BAPRAS. 2021 https://associationofbreastsurgery.org.uk/professionals/information-hub/guidelines/2021/oncoplastic-breast-reconstruction-guidelines-for-best-practice Cited for: Standards for nipple-sparing mastectomy with immediate reconstruction; operative time and hospital-stay expectations.
  3. meta analysis De La Cruz L, Moody AM, Tappy EE, Blankenship SA, Hecht EM. Overall survival, disease-free survival, local recurrence, and nipple-areolar recurrence in the setting of nipple-sparing mastectomy: a meta-analysis and systematic review. Annals of Surgical Oncology. 2015 ;22(10):3241–3249 doi:10.1245/s10434-015-4739-1 Cited for: Oncological equivalence of NSM to skin-sparing mastectomy in selected patients; low rate of nipple-areolar recurrence.
  4. cohort Galimberti V, Vicini E, Corso G, et al. Nipple-sparing and skin-sparing mastectomy: review of aims, oncological safety, and contraindications. The Breast. 2017 ;34 Suppl 1:S82–S84 doi:10.1016/j.breast.2017.06.034 Cited for: Patient-selection criteria: tumour-to-nipple distance, ptosis, breast size, smoking status; risk of nipple necrosis.